PeakSeeker: a program for interpreting genotypes of mononucleotide repeats
نویسندگان
چکیده
منابع مشابه
Quasimonomorphic Mononucleotide Repeats for High-Level Microsatellite Instability Analysis
Microsatellite instability (MSI) analysis is becoming more and more important to detect sporadic primary tumors of the MSI phenotype as well as in helping to determine Hereditary Non-Polyposis Colorectal Cancer (HNPCC) cases. After some years of conflicting data due to the absence of consensus markers for the MSI phenotype, a meeting held in Bethesda to clarify the situation proposed a set of 5...
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Protein is an essential component for life, and its synthesis is mediated by codons in any organisms on earth. While some codons encode the same amino acid, their usage is often highly biased. There are many factors that can cause the bias, but a potential effect of mononucleotide repeats, which are known to be highly mutable, on codon usage and codon pair preference is largely unknown. In this...
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Stutter products are a common artifact in the PCR amplification of frequently used genetic markers that contain mononucleotide simple sequence repeats. Despite the importance of accurate determination of nucleotide sequence and allele size, there has been little progress toward decreasing the formation of stutter products during PCR. In this study, we tested the effects of lowered extension tem...
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A G × E performance (interaction, profile) plot for showing genotype-by-environment data is discussed. Three versions of such a plot are compared: the regular performance plot; the performance plot based on coded data (environment-centered performance plot), in which the environment means of a trait are subtracted from data; and the performance plot based on data standardized in environments (e...
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ژورنال
عنوان ژورنال: BMC Research Notes
سال: 2009
ISSN: 1756-0500
DOI: 10.1186/1756-0500-2-17